Publish Time: 2022-03-30 Origin: Site
Carnitine was used to treat obesity and lose weight in the 1970s.
L-carnitine is an excellent active substance for weight loss. It is a normal component of diet. Its main function is to help long-chain fatty acids to reduce fatty acids β- Oxidation is conducive to the human body's utilization of fat and the human body's utilization of fat, including burning excess fat for energy without side effects on the body. At the same time, pay attention to strengthening exercise and consume the fat accumulated in the body to reduce weight. It belongs to a weight loss method without dieting, anorexia, fatigue and diarrhea.
The relevant experimental results showed that under the maintenance of the original living and eating habits, the subjects took L-carnitine continuously according to the specified dose of health products for 35 days. The results showed that the subjects' weight, waist circumference, hip circumference, total body fat and subcutaneous fat thickness at each point decreased, and the exercise endurance of the subjects did not decrease after the test. There were no abnormalities in the clinical symptoms and indexes of the subjects before and after the test.
After sports, the concentration of free carnitine in human muscle tissue decreased by about 20%, which can be improved by supplementing exogenous L-carnitine.
L-carnitine is the carrier of free fatty acids into mitochondria. Supplementing L-carnitine can increase the oxidation of free fatty acids to save the utilization of muscle glycogen. It is further inferred to improve aerobic capacity. Studies have reported that L-carnitine can also activate the activity of pyruvate dehydrogenase by reducing the ratio of acetyl CoA / COA, promote pyruvate oxidation and reduce lactic acid accumulation, so as to improve the sustainability of anaerobic exercise. L-carnitine can also promote the oxidation of acetoacetic acid, which may play a role in the utilization of ketones.
L-carnitine can improve the tolerance of patients during exercise, such as exercise time, maximum oxygen absorption and lactate threshold. But in fact, the research results are not consistent on whether carnitine supplementation can improve exercise ability. Early studies suggested that carnitine supplementation of 2 ~ 4 g / D could directly reduce respiratory quotient, prolong exercise time and improve critical exercise intensity. The recommended dose was 2 g / d. Large doses can cause diarrhea, and personal use should pay attention that the product cannot contain d-carnitine. Excessive d-carnitine in the tissue may replace active L-carnitine and lead to muscle atrophy. On the other hand, it is reported that L-carnitine promotes the oxidation of pyruvate, accelerates the decomposition of sugars, leads to the rapid consumption of muscle glycogen, and has a force reducing effect on exercise ability.