As one of controlled release dietary supplements in China, we can confirm some hotsale dietary supplements have be increased in 2020 and 2021, such as Melatonin 10mg controlled release tablets, Vitamin C 1000 mg /1500 mg with Zinc 15 mg controlled release tablets, L-carnitine 1000 mg controlled release tablet and probiotics 20 billion CFUs colon targeted release caplet, and the like.